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Compounds targeting bacterial, viral, or fungal pathogens by inhibiting essential biological pathways or promoting host defense mechanisms.

Modulators that regulate the cellular degradation and recycling system (autophagy), relevant in cancer, neurodegeneration, and infections.

Stabilized α-helical peptides used to mimic protein–protein interactions with enhanced cell permeability and resistance to proteolysis.

Bifunctional molecules that recruit E3 ligases to tag target proteins for degradation via the ubiquitin-proteasome system.

Electrophilic groups that covalently bind to active-site residues of target proteins, used in irreversible inhibitors and covalent PROTACs.

Monoclonal antibodies linked to cytotoxic drugs, selectively targeting cancer cells.

Inhibitors of enzymes that break down proteins (serine, cysteine, aspartic proteases).

Target microtubules, actin, or intermediate filaments to disrupt cell shape, division, and migration.

Modulators of the Wnt/β-catenin pathway and stem cell self-renewal or differentiation.

General small molecules and chemical probes for investigating biological pathways.